Product Description of Dextran CAS #9004-54-0
Dextran is a glucose polymer mainly linked by α-1,6 bonds, produced by Leuconostoc mesenteroides and related bacteria.
It is used in bioreactors, size-exclusion chromatography, and osmotic stress studies, and can also stabilize metal nanoparticles against oxidation.
Different molecular weights are used in medical applications; for example, Dextran 70 stays in the bloodstream to maintain plasma oncotic pressure but may inhibit platelet aggregation and promote fibrinolysis at high doses.
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Chemical Properties of Dextran CAS #9004-54-0
| Product Name: | Dextran |
| Synonyms: | Dextran 75,000 Mw, Pryogen Free;Dextrane2000;Dextran, high fraction, for biochemistry;MUCROSE;NATIVE DEXTRAN;POLY[(1,6)-ALPHA-D-GLUCOSE];DEXTRAN,150,000,POWDER;DEXTRAN,250,000,POWDER |
| CAS: | 9004-54-0 |
| MF: | C17H32O10 |
| MW: | 396.42998 |
| EINECS: | 232-677-5 |
| Product Categories: | Other APIs;Carbohydrates & Derivatives;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Dextrins、Sugar & Carbohydrates;Carbohydrates D-FAlphabetic;DA - DHBiochemicals and Reagents;Biostabilization AgentsCarbohydrates;Biostabilization AgentsBiochemicals and Reagents;Carbohydrates A to;Carbohydrates D-FBiochemicals and Reagents;Biochemicals and Reagents;Carbohydrates;Polysaccharide;DA - DHPolymer Standards;Alphabetic;D;Dextran;Water Soluble Polymers;DextranChromatography;DIN StandardsCertified Reference Materials (CRMs);Application CRMs;Polymer Standards;Biostabilization AgentsResearch Essentials;CarbohydratesBiochemicals and Reagents;Stabilization of Biomolecules;Core Bioreagents;Organic SolublePolymer Standards;Polymer Standards Kits;Water Soluble;Cell Separation (Centrifugation) MediaResearch Essentials;Centrifugation Media;Hematology and Histology |
| Mol File: | 9004-54-0.mol |
| Melting point | 483 °C (decomp) |
| Alpha | 198 º |
| Density | 1.00-1.20g/mL |
| Refractive index | 185 ° (C=6, H2O) |
| Storage temp | 2-8°C |
| Solubility | H2O: soluble50mg/mL, clear to very slightly hazy, colorless to faintly yellow |
| Form | Solid |
| Color | White to slightly off-white |
| PH | 46063 |
| Biological source | bacterial (Leuconostoc mesenteroides) |
| Optical activity | +208 to +233 (formaldehyde) |
| Water Solubility | Soluble in water, dimethyl sulfoxide, ethylene glycol and glycerol. |
| Merck | 142948 |
| Stability | Stable. Keep dry. Incompatible with strong oxidizing agents. |
| LogP | -4.259 (est) |
| EPA Substance Registry System | Dextran (9004-54-0) |
| Absorption | ≤0.05 at 375nm in H2O at 10% |
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Product Application of Dextran CAS #9004-54-0
Dextran is a biocompatible polysaccharide fermented by Leuconostoc mesenteroides. It is widely applied in pharmaceutical, biotech, cosmetic and food industries. In pharmacy, it serves as plasma volume expander, cryoprotectant and stabilizer for proteins and lyophilized formulations, also acts as hydrophilic carrier for controlled drug delivery. In biochemistry, it is used for cell separation, size-exclusion chromatography and cell culture. It works as thickener and humectant in cosmetics, and stabilizer, texture modifier in food formulations. Derivatized dextran can be applied in biosensor and biomaterial research.
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