5-Methoxy-2-Tetralone CAS#32940-15-1

High-Value Pharmaceutical Intermediate: Widely used in pharmaceutical R&D, particularly in the synthesis of sertraline analogues and other neurotransmitter-related compounds.

Versatile Chemical Reactivity: The substituted tetralone structure enables diverse functional modifications, supporting a broad range of synthetic applications.

Reliable Physicochemical Properties: Stable molecular structure (C₁₁H₁₂O₂) with consistent melting point (32–36 °C) ensures predictable performance in laboratory processes.

Distinct Physical Form for Easy Handling: Yellow to orange solid appearance allows for straightforward identification and convenient handling during production and research.

Products Description
5-Methoxy-2-tetralone (CAS 32940-15-1) is a substituted tetralone compound commonly used as a pharmaceutical intermediate, especially in the development and synthesis of sertraline analogues and other compounds related to neurotransmitter research. It has the molecular formula C₁₁H₁₂O₂ and is typically found as a yellow to orange solid with a melting point of approximately 32–36 °C.

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 Chemical Properties

Melting point 32-36 °C (lit.)
Boiling point 165°C/10mmHg(lit.)
density 1.124±0.06 g/cm3(Predicted)
vapor pressure 0.059Pa at 25℃
Fp >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform, Dichloromethane, Ethyl Acetate, Methanol
form Solid
color Yellowish Orange
BRN 1451623
InChIKeyMDAIAXRTLTVEOU-UHFFFAOYSA-N
LogP1.8 at 25℃
CAS DataBase Reference32940-15-1(CAS DataBase Reference)
Hazard Codes Xn
Risk Statements 20/21/22-36/37/38
Safety Statements 26-36-24/25
WGK Germany 3
HS Code 29145090

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Product Uses
5-Methoxy-2-tetralone serves as an important building block for the preparation of various biologically active compounds.

Pharmaceutical Applications: It acts as a key intermediate in the synthesis of rotigotine, a dopamine receptor agonist used for the treatment of Parkinson’s disease and restless legs syndrome.

Research and Development Uses: It is widely applied in laboratory synthesis as a starting material for developing polycyclic aromatic compounds and functionalized naphthalene derivatives.

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