Product Description of Pancreatin CAS#8049-47-6
Pancreatin is an enzyme mixture derived from fresh pig or ox pancreas, mainly containing amylase, protease, and lipase. It helps break down starch into soluble carbohydrates and hydrolyze proteins into smaller peptides, with optimal activity in neutral to slightly alkaline conditions and reduced stability in strong acid or alkali environments.
It is produced through alcohol or water extraction followed by precipitation, and contains inactive enzyme precursors that are activated in the intestine. Pancreatin is used for food digestion and hydrolysate preparation, but its oral activity may be limited due to degradation by gastric acid and pepsin.
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Pancreatin CAS#8049-47-6 Chemical Properties
| Bulk density | 400kg/m3 |
| Density | 1.4-1.52 |
| Vapor pressure | 0Pa at 25℃ |
| Storage temp | -20°C |
| Solubility | Soluble or partly soluble in water forming a slightly turbid solution; practically insoluble in ethanol (96%) and in ether . |
| Form | powder |
| Color | beige |
| PH | 5-6 (20°C, 10g/L in H2O) |
| Biological source | Porcine pancreas |
| Water Solubility | Soluble in water. Insoluble in alcohol and ether. |
| Merck | 137075 |
| Specific Activity | 8× USP specifications |
| Stability | Stable. Incompatible with alcohols, strong acids. |
Cosmetics Ingredients Functions | HAIR CONDITIONING |
| SKIN CONDITIONING | |
| LogP | -1.3 at 20℃ and pH5.7-5.8 |
| EPA Substance Registry System | Pancreatin (8049-47-6) |
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Product Application of Pancreatin CAS#8049-47-6
Pancreatin is an enzyme preparation derived from porcine pancreas that helps digest starch by converting it into dextrins and sugars. It is used as a lipase replacement therapy for conditions such as steatorrhea and pancreatic diabetes. It is also utilized in the treatment of formalin-fixed arterial graft tissues while preserving fiber integrity, as well as in contact lens processing applications.
Additionally, pancreatin is used to support the management of pancreatic insufficiency-related disorders, including after pancreatectomy, pancreatitis, and cystic fibrosis.
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