Product Description of Propylene Glycol CAS#57-55-6
Propylene Glycol USP/EP/FCC (CAS 57-55-6) delivers ≥99.5% purity and meets global pharmacopeia standards. As a USP-grade pharmaceutical excipient, it serves as a low-endotoxin (≤0.5EU/ml) solvent for injections. Certified to OECD 439, it acts as a mild, low-irritant humectant in cosmetics. The FCC-grade variant works as an antifreeze carrier for food processing, compliant with 21 CFR 184.1666. With a freezing point of -59°C (ASTM D1384) and low toxicity, it also supports industrial antifreeze applications.
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Chemical Properties of Propylene Glycol CAS#57-55-6
| Melting point | -60 °C (lit.) |
| Boiling point | 187 °C (lit.) |
| Density | 1.036 g/mL at 25 °C (lit.) |
| Vapor density | 2.62 (vs air) |
| Vapor pressure | 0.08 mm Hg ( 20 °C) |
| Refractive index | n20/D 1.432(lit.) |
| FEMA | 2940 | PROPYLENE GLYCOL |
| Fp | 225 °F |
| Storage temp. | Store at +5°C to +30°C. |
| Solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| Pka | 14.49±0.20(Predicted) |
| Form | Viscous Liquid |
| Color | APHA: ≤10 |
| Specific Gravity | 1.038 (20/20℃)1.036～1.040 |
| PH | 6-8 (100g/l, H2O, 20℃) |
| Odor | at 100.00 %. odorless very slight alcoholic |
| Odor Type | odorless |
| Optical Rotation | -0.11° (C=1.00g/100ml, CHCL3) |
| Biological source | synthetic |
| Explosive limit | 2.4-17.4%(V) |
| Water Solubility | miscible |
| Sensitive | Hygroscopic |
| Merck | 14,7855 |
| JECFA Number | 925 |
| BRN | 1340498 |
| Dielectric constant | 32.0 |
| InChIKey | DNIAPMSPPWPWGF-UHFFFAOYSA-N |
| LogP | -0.92 |
| Surface tension | 35.44mN/m at 298.15K |
| CAS DataBase Reference | 57-55-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Propylene glycol(57-55-6) |
| EPA Substance Registry System | Propylene glycol (57-55-6) |
Safety Information
| Safety Statements | 24/25 |
| WGK Germany | 1 |
| RTECS | TY2000000 |
| Autoignition Temperature | 779 °F |
| TSCA | Yes |
| HS Code | 29053200 |
| Hazardous Substances Data | 57-55-6(Hazardous Substances Data) |
| Toxicity | LD50 orally in Rabbit: 19400 - 36000 mg/kg LD50 dermal Rabbit 20800 mg/kg |
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Product Application of Propylene Glycol CAS#57-55-6
Propylene Glycol (CAS 57-55-6) is a low-toxic, highly soluble multifunctional ingredient widely applied across industries. As a USP-approved material with endotoxin ≤0.5 EU/ml, it serves as a solvent for oral and transdermal pharmaceutical formulations. In cosmetics, its OECD 439-certified moisturizing property improves hydration in lotions and serums. FCC-grade PG acts as a safe antifreeze carrier in food processing (21 CFR 184.1666), and its -59°C freezing point (ASTM D1384) enables reliable industrial antifreeze performance.
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